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OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations

Distinguishing the driver mutations from somatic mutations in a tumor genome is one of the major challenges of cancer research. This challenge is more acute and far from solved for non-coding mutations. Here we present OncodriveFML, a method designed to analyze the pattern of somatic mutations acros...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Mularoni, Loris, Sabarinathan, Radhakrishnan, Deu-Pons, Jordi, Gonzalez-Perez, Abel, López-Bigas, Núria
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910259/
https://ncbi.nlm.nih.gov/pubmed/27311963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0994-0
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