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Functional impact bias reveals cancer drivers

Identifying cancer driver genes and pathways among all somatic mutations detected in a cohort of tumors is a key challenge in cancer genomics. Traditionally, this is done by prioritizing genes according to the recurrence of alterations that they bear. However, this approach has some known limitation...

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Detalhes bibliográficos
Main Authors: Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505979/
https://ncbi.nlm.nih.gov/pubmed/22904074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks743
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