Engineered Viruses as Genome Editing Devices

Por Chen, Xiaoyu, Gonçalves, Manuel A F V
Publicado no Mol Ther (2016)

The emerging role of viral vectors as vehicles for DMD gene editing

Por Maggio, Ignazio, Chen, Xiaoyu, Gonçalves, Manuel A. F. V.
Publicado no Genome Med (2016)

Nonspaced inverted DNA repeats are preferential targets for homology-directed gene repair in mammalian cells

Por Holkers, Maarten, de Vries, Antoine A. F., Gonçalves, Manuel A. F. V.
Publicado em 2012

Histone Deacetylase Inhibition Activates Transgene Expression from Integration-Defective Lentiviral Vectors in Dividing and Non-Dividing Cells

Por Pelascini, Laetitia P.L., Janssen, Josephine M., Gonçalves, Manuel A.F.V.
Publicado em 2013

Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells

Por Maggio, Ignazio, Liu, Jin, Janssen, Josephine M., Chen, Xiaoyu, Gonçalves, Manuel A. F. V.
Publicado no Sci Rep (2016)

Rapid and Sensitive Lentivirus Vector-Based Conditional Gene Expression Assay to Monitor and Quantify Cell Fusion Activity

Por Gonçalves, Manuel A. F. V., Janssen, Josephine M., Holkers, Maarten, de Vries, Antoine A. F.
Publicado em 2010

Concerted nicking of donor and chromosomal acceptor DNA promotes homology-directed gene targeting in human cells

Por Gonçalves, Manuel A. F. V., van Nierop, Gijsbert P., Holkers, Maarten, de Vries, Antoine A. F.
Publicado em 2012

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells

Por Maggio, Ignazio, Holkers, Maarten, Liu, Jin, Janssen, Josephine M., Chen, Xiaoyu, Gonçalves, Manuel A. F. V.
Publicado em 2014

Probing the impact of chromatin conformation on genome editing tools

Por Chen, Xiaoyu, Rinsma, Marrit, Janssen, Josephine M., Liu, Jin, Maggio, Ignazio, Gonçalves, Manuel A.F.V.
Publicado no Nucleic Acids Res (2016)

Histone Deacetylase Inhibition Rescues Gene Knockout Levels Achieved with Integrase-Defective Lentiviral Vectors Encoding Zinc-Finger Nucleases

Por Pelascini, Laetitia P.L., Maggio, Ignazio, Liu, Jin, Holkers, Maarten, Cathomen, Toni, Gonçalves, Manuel A.F.V.
Publicado em 2013

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations

Por Maggio, Ignazio, Stefanucci, Luca, Janssen, Josephine M., Liu, Jin, Chen, Xiaoyu, Mouly, Vincent, Gonçalves, Manuel A.F.V.
Publicado no Nucleic Acids Res (2016)

Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease

Por van Nierop, Gijsbert P., de Vries, Antoine A. F., Holkers, Maarten, Vrijsen, Krijn R., Gonçalves, Manuel A. F. V.
Publicado em 2009

Targeted Chromosomal Insertion of Large DNA into the Human Genome by a Fiber-Modified High-Capacity Adenovirus-Based Vector System

Por Gonçalves, Manuel A. F. V., Holkers, Maarten, van Nierop, Gijsbert P., Wieringa, Roeland, Pau, Maria G., de Vries, Antoine A. F.
Publicado em 2008

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells

Por Holkers, Maarten, Maggio, Ignazio, Liu, Jin, Janssen, Josephine M., Miselli, Francesca, Mussolino, Claudio, Recchia, Alessandra, Cathomen, Toni, Gonçalves, Manuel A. F. V.
Publicado em 2013

Efficient Generation and Amplification of High-Capacity Adeno-Associated Virus/Adenovirus Hybrid Vectors

Por Gonçalves, Manuel A. F. V., van der Velde, Ietje, Janssen, Josephine M., Maassen, Bram T. H., Heemskerk, Evert H., Opstelten, Dirk-Jan E., Knaän-Shanzer, Shoshan, Valerio, Dinko, de Vries, Antoine A. F.
Publicado em 2002

Transfer of the Full-Length Dystrophin-Coding Sequence into Muscle Cells by a Dual High-Capacity Hybrid Viral Vector with Site-Specific Integration Ability

Por Gonçalves, Manuel A. F. V., van Nierop, Gijsbert P., Tijssen, Marloes R., Lefesvre, Pierre, Knaän-Shanzer, Shoshan, van der Velde, Ietje, van Bekkum, Dirk W., Valerio, Dinko, de Vries, Antoine A. F.
Publicado em 2005