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Nonspaced inverted DNA repeats are preferential targets for homology-directed gene repair in mammalian cells
DNA repeats constitute potential sites for the nucleation of secondary structures such as hairpins and cruciforms. Studies performed mostly in bacteria and yeast showed that these noncanonical DNA structures are breakage-prone, making them candidate targets for cellular DNA repair pathways. Possible...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300023/ https://ncbi.nlm.nih.gov/pubmed/22080552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr976 |
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