Probing the impact of chromatin conformation on genome editing tools

Transcription activator-like effector nucleases (TALENs) and RNA-guided nucleases derived from clustered, regularly interspaced, short palindromic repeats (CRISPR)-Cas9 systems have become ubiquitous genome editing tools. Despite this, the impact that distinct high-order chromatin conformations have...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chen, Xiaoyu, Rinsma, Marrit, Janssen, Josephine M., Liu, Jin, Maggio, Ignazio, Gonçalves, Manuel A.F.V.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Synthetic Biology and Bioengineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291272/
https://ncbi.nlm.nih.gov/pubmed/27280977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw524
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