Loading...

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells

CRISPR/Cas9-derived RNA-guided nucleases (RGNs) are DNA targeting systems, which are rapidly being harnessed for gene regulation and gene editing purposes in model organisms and cell lines. As bona fide gene delivery vehicles, viral vectors may be particularly fit to broaden the applicability of RGN...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Maggio, Ignazio, Holkers, Maarten, Liu, Jin, Janssen, Josephine M., Chen, Xiaoyu, Gonçalves, Manuel A. F. V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037712/
https://ncbi.nlm.nih.gov/pubmed/24870050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05105
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!