Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics

por Gollapudi, Sampath K., Chandra, Murali
Publicado 2012

The Effect of Cardiomyopathy Mutation (R97L) in Mouse Cardiac Troponin T on the Muscle Length-mediated Recruitment of Crossbridges is Modified Divergently by α- and β-myosin Heavy...

por Gollapudi, Sampath K., Chandra, Murali
Publicado en Arch Biochem Biophys (2016)

Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain

por Gollapudi, Sampath K., Chandra, Murali
Publicado en Front Physiol (2016)

Rat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms

por Chandra, Vikram, Gollapudi, Sampath K., Chandra, Murali
Publicado en Am J Physiol Heart Circ Physiol (2015)

The Tropomyosin Binding Region of Cardiac Troponin T Modulates Crossbridge Recruitment Dynamics in Rat Cardiac Muscle Fibers

por Gollapudi, Sampath K., Gallon, Clare E., Chandra, Murali
Publicado 2013

The functional effect of dilated cardiomyopathy mutation (R144W) in mouse cardiac troponin T is differently affected by α- and β-myosin heavy chain isoforms

por Gollapudi, Sampath K., Tardiff, Jil C., Chandra, Murali
Publicado en Am J Physiol Heart Circ Physiol (2015)

Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers

por Mickelson, Alexis V., Gollapudi, Sampath K., Chandra, Murali
Publicado en Am J Physiol Heart Circ Physiol (2017)

Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca(2+) Sensitivity

por Gollapudi, Sampath K., Reda, Sherif M., Chandra, Murali
Publicado en Biophys J (2017)

Developmental increase in β-MHC enhances sarcomere length–dependent activation in the myocardium

por Reda, Sherif M., Gollapudi, Sampath K., Chandra, Murali
Publicado en J Gen Physiol (2019)

The N-Terminal Extension of Cardiac Troponin T Stabilizes the Blocked State of Cardiac Thin Filament

por Gollapudi, Sampath K., Mamidi, Ranganath, Mallampalli, Sri Lakshmi, Chandra, Murali
Publicado 2012

Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics

por Mamidi, Ranganath, Gollapudi, Sampath K., Mallampalli, Sri Lakshmi, Chandra, Murali
Publicado 2012

Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems

por Gollapudi, Sampath K., Yu, Ming, Gan, Qing-Fen, Nag, Suman
Publicado en J Biol Chem (2020)

Deletion of 1–43 amino acids in cardiac myosin essential light chain blunts length dependency of Ca(2+) sensitivity and cross-bridge detachment kinetics

por Michael, John Jeshurun, Gollapudi, Sampath K., Ford, Steven J., Kazmierczak, Katarzyna, Szczesna-Cordary, Danuta, Chandra, Murali
Publicado 2013