Loading...
Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers
The present study investigated the functional consequences of the human hypertrophic cardiomyopathy (HCM) mutation A28V in cardiac troponin T (TnT). The A28V mutation is located within the NH(2) terminus of TnT, a region known to be important for full activation of cardiac thin filaments. The functi...
Saved in:
| Published in: | Am J Physiol Heart Circ Physiol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283911/ https://ncbi.nlm.nih.gov/pubmed/27769999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00487.2016 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|