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Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain
Many studies have demonstrated that depressed myofilament Ca(2+) sensitivity is common to dilated cardiomyopathy (DCM) in humans. However, it remains unclear whether a single determinant—such as myofilament Ca(2+) sensitivity—is sufficient to characterize all cases of DCM because the severity of dis...
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| Publié dans: | Front Physiol |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047882/ https://ncbi.nlm.nih.gov/pubmed/27757084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00443 |
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