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Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics

Previous studies of cardiomyopathy-related mutations in cardiac troponin C (cTnC)—L29Q and G159D—have shown diverse findings. The link between such mutant effects and their divergent impact on cardiac phenotypes has remained elusive due to lack of studies on contractile dynamics. We hypothesized tha...

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Detalhes bibliográficos
Main Authors: Gollapudi, Sampath K., Chandra, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447348/
https://ncbi.nlm.nih.gov/pubmed/23008774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/824068
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