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Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics

Previous studies of cardiomyopathy-related mutations in cardiac troponin C (cTnC)—L29Q and G159D—have shown diverse findings. The link between such mutant effects and their divergent impact on cardiac phenotypes has remained elusive due to lack of studies on contractile dynamics. We hypothesized tha...

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Main Authors: Gollapudi, Sampath K., Chandra, Murali
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447348/
https://ncbi.nlm.nih.gov/pubmed/23008774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/824068
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