Auxin and Tryptophan Homeostasis Are Facilitated by the ISS1/VAS1 Aromatic Aminotransferase in Arabidopsis

Por Pieck, Michael, Yuan, Youxi, Godfrey, Jason, Fisher, Christopher, Zolj, Sanda, Vaughan, Dylan, Thomas, Nicholas, Wu, Connie, Ramos, Julian, Lee, Norman, Normanly, Jennifer, Celenza, John L.
Publicado no Genetics (2015)

Molecular heterogeneity and receptor co-amplification drive resistance to targeted therapy in MET-amplified esophagogastric cancer

Por Kwak, Eunice L., Ahronian, Leanne G., Siravegna, Giulia, Mussolin, Benedetta, Godfrey, Jason T., Clark, Jeffrey W., Blaszkowsky, Lawrence S., Ryan, David P., Lennerz, Jochen K., Iafrate, A. John, Bardelli, Alberto, Hong, Theodore S., Corcoran, Ryan B.
Publicado no Cancer Discov (2015)

TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF-Mutant Melanoma

Por Corcoran, Ryan B., Rothenberg, Stephen Michael, Hata, Aaron N., Faber, Anthony C., Piris, Adriano, Nazarian, Rosalynn M., Brown, Ronald D., Godfrey, Jason T., Winokur, Daniel, Walsh, John, Mino-Kenudson, Mari, Maheswaran, Shyamala, Settleman, Jeffrey, Wargo, Jennifer A., Flaherty, Keith T., Haber, Daniel A., Engelman, Jeffrey A.
Publicado em 2013

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

Por Corcoran, Ryan B., Cheng, Katherine A., Hata, Aaron N., Faber, Anthony C., Ebi, Hiromichi, Coffee, Erin M., Greninger, Patricia, Brown, Ronald D., Godfrey, Jason T., Cohoon, Travis J., Song, Youngchul, Lifshits, Eugene, Hung, Kenneth E., Shioda, Toshi, Dias-Santagata, Dora, Singh, Anurag, Settleman, Jeffrey, Benes, Cyril H., Mino-Kenudson, Mari, Wong, Kwok-Kin, Engelman, Jeffrey A.
Publicado em 2012

Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations

Por Ahronian, Leanne G., Sennott, Erin M., Van Allen, Eliezer M., Wagle, Nikhil, Kwak, Eunice L., Faris, Jason E., Godfrey, Jason T., Nishimura, Koki, Lynch, Kerry D., Mermel, Craig H., Lockerman, Elizabeth L., Kalsy, Anuj, Gurski, Joseph M., Bahl, Samira, Anderka, Kristin, Green, Lisa M., Lennon, Niall J., Huynh, Tiffany G., Mino-Kenudson, Mari, Getz, Gad, Dias-Santagata, Dora, Iafrate, A. John, Engelman, Jeffrey A., Garraway, Levi A., Corcoran, Ryan B.
Publicado no Cancer Discov (2015)

Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer

Por Oddo, Daniele, Sennott, Erin M., Barault, Ludovic, Valtorta, Emanuele, Arena, Sabrina, Cassingena, Andrea, Filiciotto, Genny, Marzolla, Giulia, Elez, Elena, van Geel, Robin M.J.M., Bartolini, Alice, Crisafulli, Giovanni, Boscaro, Valentina, Godfrey, Jason T., Buscarino, Michela, Cancelliere, Carlotta, Linnebacher, Michael, Corti, Giorgio, Truini, Mauro, Siravegna, Giulia, Grasselli, Julieta, Gallicchio, Margherita, Bernards, René, Schellens, Jan H.M., Tabernero, Josep, Engelman, Jeffrey A., Sartore-Bianchi, Andrea, Bardelli, Alberto, Siena, Salvatore, Corcoran, Ryan B., Di Nicolantonio, Federica
Publicado no Cancer Res (2016)

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit

Por Zhu, Zehua, Aref, Amir R., Cohoon, Travis J., Barbie, Thanh U., Imamura, Yu, Yang, Shenghong, Moody, Susan E., Shen, Rhine R., Schinzel, Anna C., Thai, Tran C., Reibel, Jacob B., Tamayo, Pablo, Godfrey, Jason T., Qian, Zhi Rong, Page, Asher N., Maciag, Karolina, Chan, Edmond M., Silkworth, Whitney, Labowsky, Mary T., Rozhansky, Lior, Mesirov, Jill P., Gillanders, William E., Ogino, Shuji, Hacohen, Nir, Gaudet, Suzanne, Eck, Michael J., Engelman, Jeffrey A., Corcoran, Ryan B., Wong, Kwok-Kin, Hahn, William C., Barbie, David A.
Publicado em 2014