An evidence-based review of obatoclax mesylate in the treatment of hematological malignancies

Por Goard, Carolyn A, Schimmer, Aaron D
Publicado em 2013

Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance

Por Martirosyan, Anna, Clendening, James W, Goard, Carolyn A, Penn, Linda Z
Publicado em 2010

A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity

Por Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Wang, Xiaoming, Goard, Carolyn A., Jhas, Bozhena, Schimmer, Aaron D.
Publicado em 2014

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death

Por Pandyra, Aleksandra A., Mullen, Peter J., Goard, Carolyn A., Ericson, Elke, Sharma, Piyush, Kalkat, Manpreet, Yu, Rosemary, Pong, Janice T., Brown, Kevin R., Hart, Traver, Gebbia, Marinella, Lang, Karl S., Giaever, Guri, Nislow, Corey, Moffat, Jason, Penn, Linda Z.
Publicado no Oncotarget (2015)

Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human Leukemic Cells

Por Xu, G. Wei, Toth, Julia I., da Silva, Sara R., Paiva, Stacey-Lynn, Lukkarila, Julie L., Hurren, Rose, Maclean, Neil, Sukhai, Mahadeo A., Bhattacharjee, Rabindra N., Goard, Carolyn A., Gunning, Patrick T., Dhe-Paganon, Sirano, Petroski, Matthew D., Schimmer, Aaron D.
Publicado em 2014

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Por Sriskanthadevan, Shrivani, Jeyaraju, Danny V., Chung, Timothy E., Prabha, Swayam, Xu, Wei, Skrtic, Marko, Jhas, Bozhena, Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Jitkova, Yulia, Sukhai, Mahadeo A., Lin, Feng-Hsu, Maclean, Neil, Laister, Rob, Goard, Carolyn A., Mullen, Peter J., Xie, Stephanie, Penn, Linda Z., Rogers, Ian M., Dick, John E., Minden, Mark D., Schimmer, Aaron D.
Publicado no Blood (2015)