A Membrane-proximal, C-terminal α-Helix Is Required for Plasma Membrane Localization and Function of the G Protein-coupled Receptor (GPCR) TGR5

по Spomer, Lina, Gertzen, Christoph G. W., Schmitz, Birte, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena
Опубликовано 2014

Identification of a Conserved Interface of Human Immunodeficiency Virus Type 1 and Feline Immunodeficiency Virus Vifs with Cullin 5

по Gu, Qinyong, Zhang, Zeli, Gertzen, Christoph G. W., Häussinger, Dieter, Gohlke, Holger, Münk, Carsten
Опубликовано в: J Virol (2018)

Interaction of Ochratoxin A and Its Thermal Degradation Product 2′R-Ochratoxin A with Human Serum Albumin

по Sueck, Franziska, Poór, Miklós, Faisal, Zelma, Gertzen, Christoph G. W., Cramer, Benedikt, Lemli, Beáta, Kunsági-Máté, Sándor, Gohlke, Holger, Humpf, Hans-Ulrich
Опубликовано в: Toxins (Basel) (2018)

Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication

по Klinker, Stefan, Stindt, Sabine, Gremer, Lothar, Bode, Johannes G., Gertzen, Christoph G. W., Gohlke, Holger, Weiergräber, Oliver H., Hoffmann, Silke, Willbold, Dieter
Опубликовано в: J Biol Chem (2019)

Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity

по Reßing, Nina, Marquardt, Viktoria, Gertzen, Christoph G. W., Schöler, Andrea, Schramm, Alexander, Kurz, Thomas, Gohlke, Holger, Aigner, Achim, Remke, Marc, Hansen, Finn K.
Опубликовано в: Medchemcomm (2018)

Semisynthetic Analogs of the Antibiotic Fidaxomicin—Design, Synthesis, and Biological Evaluation

по Dorst, Andrea, Berg, Regina, Gertzen, Christoph G. W., Schäfle, Daniel, Zerbe, Katja, Gwerder, Myriam, Schnell, Simon D., Sander, Peter, Gohlke, Holger, Gademann, Karl
Опубликовано в: ACS Med Chem Lett (2020)

Structural assemblies of the di- and oligomeric G-protein coupled receptor TGR5 in live cells: an MFIS-FRET and integrative modelling study

по Greife, Annemarie, Felekyan, Suren, Ma, Qijun, Gertzen, Christoph G. W., Spomer, Lina, Dimura, Mykola, Peulen, Thomas O., Wöhler, Christina, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena, Seidel, Claus A. M.
Опубликовано в: Sci Rep (2016)

Synthesis, Biological Evaluation and Molecular Modeling of Substituted Indeno[1,2-b]indoles as Inhibitors of Human Protein Kinase CK2

по Alchab, Faten, Ettouati, Laurent, Bouaziz, Zouhair, Bollacke, Andre, Delcros, Jean-Guy, Gertzen, Christoph G.W., Gohlke, Holger, Pinaud, Noël, Marchivie, Mathieu, Guillon, Jean, Fenet, Bernard, Jose, Joachim, Le Borgne, Marc
Опубликовано в: Pharmaceuticals (Basel) (2015)

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

по Lin, Minhui, Nebral, Karin, Gertzen, Christoph G. W., Ganmore, Ithamar, Haas, Oskar A., Bhatia, Sanil, Fischer, Ute, Kuhlen, Michaela, Gohlke, Holger, Izraeli, Shai, Trka, Jan, Hu, Jianda, Borkhardt, Arndt, Hauer, Julia, Auer, Franziska
Опубликовано в: Leukemia (2019)

A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family

по Perez-Garcia, Pablo, Kobus, Stefanie, Gertzen, Christoph G. W., Hoeppner, Astrid, Holzscheck, Nicholas, Strunk, Christoph Heinrich, Huber, Harald, Jaeger, Karl-Erich, Gohlke, Holger, Kovacic, Filip, Smits, Sander H. J., Streit, Wolfgang R., Chow, Jennifer
Опубликовано в: Commun Biol (2021)