A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes

by Funk, Colin D., Ardakani, Ali
Published in Front Pharmacol (2020)

A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic

by Funk, Colin D., Laferrière, Craig, Ardakani, Ali
Published in Front Pharmacol (2020)

Target Product Profile Analysis of COVID-19 Vaccines in Phase III Clinical Trials and Beyond: An Early 2021 Perspective

by Funk, Colin D., Laferrière, Craig, Ardakani, Ali
Published in Viruses (2021)

Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase

by Johnson, Eric N., Brass, Lawrence F., Funk, Colin D.
Published 1998

Pulmonary Oxidative Stress Is Increased in Cyclooxygenase-2 Knockdown Mice with Mild Pulmonary Hypertension Induced by Monocrotaline

by Seta, Francesca, Rahmani, Mahboubeh, Turner, Patricia V., Funk, Colin D.
Published 2011

Perivascular adipose tissue–derived extracellular vesicle miR-221-3p mediates vascular remodeling

by Li, Xinzhi, Ballantyne, Laurel L., Yu, Ying, Funk, Colin D.
Published in FASEB J (2019)

Absence of 12/15 Lipoxygenase Reduces Brain Oxidative Stress in Apolipoprotein E-Deficient Mice

by Chinnici, Cinzia M., Yao, Yuemang, Ding, Tao, Funk, Colin D., Praticò, Domenico
Published 2005

Dual 12/15- and 5-Lipoxygenase Deficiency in Macrophages Alters Arachidonic Acid Metabolism and Attenuates Peritonitis and Atherosclerosis in ApoE Knock-out Mice

by Poeckel, Daniel, Zemski Berry, Karin A., Murphy, Robert C., Funk, Colin D.
Published 2009

Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency

by Sin, Yuan Yan, Price, Phillipe R., Ballantyne, Laurel L., Funk, Colin D.
Published in Sci Rep (2017)

Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice

by Sin, Yuan Yan, Ballantyne, Laurel L., Richmond, Christopher R., Funk, Colin D.
Published in Mol Ther Nucleic Acids (2017)

The Murine Angiotensin II-Induced Abdominal Aortic Aneurysm Model: Rupture Risk and Inflammatory Progression Patterns

by Cao, Richard Y., Amand, Tim, Ford, Matthew D., Piomelli, Ugo, Funk, Colin D.
Published 2010

Actin Polymerization in Macrophages in Response to Oxidized LDL and Apoptotic Cells: Role of 12/15-Lipoxygenase and Phosphoinositide 3-Kinase

by Miller, Yury I., Worrall, Dorothy S., Funk, Colin D., Feramisco, James R., Witztum, Joseph L.
Published 2003

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice

by Bleich, David, Chen, Songyuan, Zipser, Brian, Sun, Duxin, Funk, Colin D., Nadler, Jerry L.
Published 1999

Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice

by Cao, Richard Yang, Eves, Robert, Jia, Lilly, Funk, Colin D., Jia, Zongchao, Mak, Alan S.
Published in PLoS One (2017)

Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting

by Sun, Xiujun, Funk, Colin D., Deng, Chengjun, Sahu, Arvind, Lambris, John D., Song, Wen-Chao
Published 1999

Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

by Cheng, Yan, Wang, Miao, Yu, Ying, Lawson, John, Funk, Colin D., FitzGerald, Garret A.
Published 2006

Genomic and lipidomic analyses differentiate the compensatory roles of two COX isoforms during systemic inflammation in mice(1),(2)

by Li, Xinzhi, Mazaleuskaya, Liudmila L., Ballantyne, Laurel L., Meng, Hu, FitzGerald, Garret A., Funk, Colin D.
Published in J Lipid Res (2018)

Differential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions

by Li, Xinzhi, Mazaleuskaya, Liudmila L., Ballantyne, Laurel L., Meng, Hu, FitzGerald, Garret A., Funk, Colin D.
Published in FASEB J (2018)

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor γ1

by Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley
Published 2001

Characterization of the Cysteinyl Leukotriene 2 Receptor in Novel Expression Sites of the Gastrointestinal Tract

by Barajas-Espinosa, Alma, Ochoa-Cortes, Fernando, Moos, Michael P., Daniel Ramirez, F., Vanner, Stephen J., Funk, Colin D.
Published 2011