Affibody molecules as engineered protein drugs

Por Frejd, Fredrik Y, Kim, Kyu-Tae
Publicado no Exp Mol Med (2017)

Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds

Por Malm, Magdalena, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John
Publicado no MAbs (2016)

In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor

Por Seijsing, Johan, Yu, Shengze, Frejd, Fredrik Y, Höiden-Guthenberg, Ingmarie, Gräslund, Torbjörn
Publicado no Sci Rep (2018)

Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity

Por Fleetwood, Filippa, Klint, Susanne, Hanze, Martin, Gunneriusson, Elin, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John
Publicado no Sci Rep (2014)

Cellular Effects of HER3-Specific Affibody Molecules

Por Göstring, Lovisa, Malm, Magdalena, Höidén-Guthenberg, Ingmarie, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John, Gedda, Lars
Publicado em 2012

Imaging of CAIX-expressing xenografts in vivo using (99m)Tc-HEHEHE-ZCAIX:1 Affibody molecule

Por HONARVAR, HADIS, GAROUSI, JAVAD, GUNNERIUSSON, ELIN, HÖIDÉN-GUTHENBERG, INGMARIE, ALTAI, MOHAMED, WIDSTRÖM, CHARLES, TOLMACHEV, VLADIMIR, FREJD, FREDRIK Y.
Publicado no Int J Oncol (2014)

In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin-binding therapeutic affibody construct

Por Bass, Tarek Z., Rosestedt, Maria, Mitran, Bogdan, Frejd, Fredrik Y., Löfblom, John, Tolmachev, Vladimir, Ståhl, Stefan, Orlova, Anna
Publicado no Sci Rep (2017)

An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein

Por Seijsing, Johan, Lindborg, Malin, Höidén-Guthenberg, Ingmarie, Bönisch, Heiko, Guneriusson, Elin, Frejd, Fredrik Y., Abrahmsén, Lars, Ekblad, Caroline, Löfblom, John, Uhlén, Mathias, Gräslund, Torbjörn
Publicado no Proc Natl Acad Sci U S A (2014)

Inhibiting HER3-Mediated Tumor Cell Growth with Affibody Molecules Engineered to Low Picomolar Affinity by Position-Directed Error-Prone PCR-Like Diversification

Por Malm, Magdalena, Kronqvist, Nina, Lindberg, Hanna, Gudmundsdotter, Lindvi, Bass, Tarek, Frejd, Fredrik Y., Höidén-Guthenberg, Ingmarie, Varasteh, Zohreh, Orlova, Anna, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John
Publicado em 2013

Correction: Inhibiting HER3-Mediated Tumor Cell Growth with Affibody Molecules Engineered to Low Picomolar Affinity by Position-Directed Error-Prone PCR-Like Diversification

Por Malm, Magdalena, Kronqvist, Nina, Lindberg, Hanna, Gudmundsdotter, Lindvi, Bass, Tarek, Frejd, Fredrik Y., Höidén-Guthenberg, Ingmarie, Varasteh, Zohreh, Orlova, Anna, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John
Publicado em 2013