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Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds

The human epidermal growth factor receptor 3 (HER3) has in recent years been recognized as a key node in the complex signaling network of many different cancers. It is implicated in de novo and acquired resistance against therapies targeting other growth factor receptors, e.g., EGFR, HER2, and it is...

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Foilsithe in:MAbs
Main Authors: Malm, Magdalena, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058629/
https://ncbi.nlm.nih.gov/pubmed/27532938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1212147
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