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In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin-binding therapeutic affibody construct
Overexpression of human epidermal growth factor receptor 3 (HER3) is involved in resistance to several therapies for malignant tumours. Currently, several anti-HER3 monoclonal antibodies are under clinical development. We introduce an alternative approach to HER3-targeted therapy based on engineered...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322329/ https://ncbi.nlm.nih.gov/pubmed/28230065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43118 |
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