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Affibody-mediated PET imaging of HER3 expression in malignant tumours

Human epidermal growth factor receptor 3 (HER3) is involved in the progression of various cancers and in resistance to therapies targeting the HER family. In vivo imaging of HER3 expression would enable patient stratification for anti-HER3 immunotherapy. Key challenges with HER3-targeting are the re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rosestedt, Maria, Andersson, Ken G., Mitran, Bogdan, Tolmachev, Vladimir, Löfblom, John, Orlova, Anna, Ståhl, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609989/
https://ncbi.nlm.nih.gov/pubmed/26477646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15226
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