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Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds

The human epidermal growth factor receptor 3 (HER3) has in recent years been recognized as a key node in the complex signaling network of many different cancers. It is implicated in de novo and acquired resistance against therapies targeting other growth factor receptors, e.g., EGFR, HER2, and it is...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Malm, Magdalena, Frejd, Fredrik Y., Ståhl, Stefan, Löfblom, John
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058629/
https://ncbi.nlm.nih.gov/pubmed/27532938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1212147
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