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In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor
Lowering the total level of Immunoglobulin G (IgG) in circulation is a promising general treatment option for many autoimmune diseases driven by pathogenic autoantibodies. The half-life of IgG in circulation is unusually long as a consequence of its interaction with the neonatal Fc receptor (FcRn),...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865129/ https://ncbi.nlm.nih.gov/pubmed/29572538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23481-5 |
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