Imaging of CAIX-expressing xenografts in vivo using (99m)Tc-HEHEHE-ZCAIX:1 Affibody molecule

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme involved in regulation of tissue pH balance. In cancer, CAIX expression is associated with tumor hypoxia. CAIX is also overexpressed in renal cell carcinoma and is a molecular target for the therapeutic antibody cG250 (girentuximab). Radionuclid...

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Publicado en:Int J Oncol
Autores principales: HONARVAR, HADIS, GAROUSI, JAVAD, GUNNERIUSSON, ELIN, HÖIDÉN-GUTHENBERG, INGMARIE, ALTAI, MOHAMED, WIDSTRÖM, CHARLES, TOLMACHEV, VLADIMIR, FREJD, FREDRIK Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277246/
https://ncbi.nlm.nih.gov/pubmed/25434612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2782
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