A protein phosphatase functions to recycle RNA polymerase II

by Cho, Helen, Kim, Tae-Kyung, Mancebo, Helena, Lane, William S., Flores, Osvaldo, Reinberg, Danny
Published 1999

Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication

by Flores, Osvaldo, Lee, Gary, Kessler, Joseph, Miller, Michael, Schlief, William, Tomassini, Joanne, Hazuda, Daria
Published 1999

Characterization of a Novel Small Molecule Subtype Specific Estrogen-Related Receptor α Antagonist in MCF-7 Breast Cancer Cells

by Chisamore, Michael J., Cunningham, Michael E., Flores, Osvaldo, Wilkinson, Hilary A., Chen, J. Don
Published 2009

Persistent Replication of Hepatitis C Virus Replicons Expressing the β-Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

by Murray, Edward M., Grobler, Jay A., Markel, Eric J., Pagnoni, Marco F., Paonessa, Giacomo, Simon, Adam J., Flores, Osvaldo A.
Published 2003

Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants

by Lam, Angela M., Ren, Suping, Espiritu, Christine, Kelly, Mollie, Lau, Vincent, Zheng, Lingjie, Hartman, George D., Flores, Osvaldo A., Klumpp, Klaus
Published in Antimicrob Agents Chemother (2017)

Non-invasive muscle contraction assay to study rodent models of sarcopenia

by Chiu, Chi-Sung, Weber, Hans, Adamski, Sharon, Rauch, Albert, Gentile, Michael A, Alves, Stephen E, Kath, Gary, Flores, Osvaldo, Wilkinson, Hilary A
Published 2011

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

by Mancebo, Helena S.Y., Lee, Gary, Flygare, John, Tomassini, Joanne, Luu, Percy, Zhu, Yuerong, Peng, Junmin, Blau, Carol, Hazuda, Daria, Price, David, Flores, Osvaldo
Published 1997

Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus

by Lam, Angela M., Espiritu, Christine, Vogel, Robert, Ren, Suping, Lau, Vincent, Kelly, Mollie, Kuduk, Scott D., Hartman, George D., Flores, Osvaldo A., Klumpp, Klaus
Published in Antimicrob Agents Chemother (2018)

High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein

by Klumpp, Klaus, Lam, Angela M., Lukacs, Christine, Vogel, Robert, Ren, Suping, Espiritu, Christine, Baydo, Ruth, Atkins, Kateri, Abendroth, Jan, Liao, Guochun, Efimov, Andrey, Hartman, George, Flores, Osvaldo A.
Published in Proc Natl Acad Sci U S A (2015)

Replication Fitness and NS5B Drug Sensitivity of Diverse Hepatitis C Virus Isolates Characterized by Using a Transient Replication Assay

by Ludmerer, Steven W., Graham, Donald J., Boots, Evelyn, Murray, Edward M., Simcoe, Amy, Markel, Eric J., Grobler, Jay A., Flores, Osvaldo A., Olsen, David B., Hazuda, Daria J., LaFemina, Robert L.
Published 2005

Inhibitory Effect of 2′-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

by Tomassini, Joanne E., Getty, Krista, Stahlhut, Mark W., Shim, Sung, Bhat, Balkrishen, Eldrup, Anne B., Prakash, Thazha P., Carroll, Steven S., Flores, Osvaldo, MacCoss, Malcolm, McMasters, Daniel R., Migliaccio, Giovanni, Olsen, David B.
Published 2005

Generation and Selection of Novel Fully Human Monoclonal Antibodies That Neutralize Dickkopf-1 (DKK1) Inhibitory Function in Vitro and Increase Bone Mass in Vivo

by Glantschnig, Helmut, Hampton, Richard A., Lu, Ping, Zhao, Jing Z., Vitelli, Salvatore, Huang, Lingyi, Haytko, Peter, Cusick, Tara, Ireland, Cheryl, Jarantow, Stephen W., Ernst, Robin, Wei, Nan, Nantermet, Pascale, Scott, Kevin R., Fisher, John E., Talamo, Fabio, Orsatti, Laura, Reszka, Alfred A., Sandhu, Punam, Kimmel, Donald, Flores, Osvaldo, Strohl, William, An, Zhiqiang, Wang, Fubao
Published 2010

A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties

by Olsen, David B., Eldrup, Anne B., Bartholomew, Linda, Bhat, Balkrishen, Bosserman, Michele R., Ceccacci, Alessandra, Colwell, Lawrence F., Fay, John F., Flores, Osvaldo A., Getty, Krista L., Grobler, Jay A., LaFemina, Robert L., Markel, Eric J., Migliaccio, Giovanni, Prhavc, Marija, Stahlhut, Mark W., Tomassini, Joanne E., MacCoss, Malcolm, Hazuda, Daria J., Carroll, Steven S.
Published 2004