Persistent Replication of Hepatitis C Virus Replicons Expressing the β-Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

Progress toward development of better therapies for the treatment of hepatitis C virus (HCV) infection has been hampered by poor understanding of HCV biology and the lack of biological assays suitable for drug screening. Here we describe a powerful HCV replication system that employs HCV replicons e...

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Detalhes bibliográficos
Main Authors: Murray, Edward M., Grobler, Jay A., Markel, Eric J., Pagnoni, Marco F., Paonessa, Giacomo, Simon, Adam J., Flores, Osvaldo A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149762/
https://ncbi.nlm.nih.gov/pubmed/12584317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.2928-2935.2003
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