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Persistent Replication of Hepatitis C Virus Replicons Expressing the β-Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

Progress toward development of better therapies for the treatment of hepatitis C virus (HCV) infection has been hampered by poor understanding of HCV biology and the lack of biological assays suitable for drug screening. Here we describe a powerful HCV replication system that employs HCV replicons e...

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Udgivet i:J Virol
Principais autores: Murray, Edward M., Grobler, Jay A., Markel, Eric J., Pagnoni, Marco F., Paonessa, Giacomo, Simon, Adam J., Flores, Osvaldo A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12584317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.5.2928-2935.2003
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