STUDIES DIRECTED TOWARD THE SYNTHESIS OF NAKADOMARIN A

por Haimowitz, Thomas, Fitzgerald, Mark E., Winkler, Jeffrey D.
Publicado 2011

A Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization

por Fitzgerald, Mark E., Mulrooney, Carol A., Duvall, Jeremy R., Wei, Jingqiang, Suh, Byung-Chul, Akella, Lakshmi B., Vrcic, Anita, Marcaurelle, Lisa A.
Publicado 2012

Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors

por Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.
Publicado en J Infect Dis (2015)

Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C-Glycosides

por Gerard, Baudouin, Dandapani, Sivaraman, Duvall, Jeremy R., Fitzgerald, Mark E., Kesavan, Sarathy, Lee, Maurice D., Lowe, Jason T., Marié, Jean-Charles, Pandya, Bhaumik A., Suh, Byung-Chul, O’Shea, Morgan Welzel, Dombrowski, Michael, Hamann, Diane, Lemercier, Berenice, Murillo, Tiffanie, Akella, Lakshmi B., Foley, Michael A., Marcaurelle, Lisa A.
Publicado 2013

Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile

por Duvall, Jeremy R., Bedard, Leanne, Naylor-Olsen, Adel M., Manson, Abigail L., Bittker, Joshua A., Sun, Wenye, Fitzgerald, Mark E., He, Zhenmin, Lee, Maurice D., Marie, Jean-Charles, Muncipinto, Giovanni, Rush, Diane, Xu, Deming, Xu, Huisheng, Zhang, Mingliang, Earl, Ashlee M., Palmer, Michelle A., Foley, Michael A., Vacca, Joseph P., Scherer, Christina A.
Publicado en ACS Infect Dis (2017)

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents

por Comer, Eamon, Beaudoin, Jennifer A., Kato, Nobutaka, Fitzgerald, Mark E., Heidebrecht, Richard W., Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E., Lukens, Amanda K., Wiegand, Roger C., Wirth, Dyann F., Palmer, Michelle A., Foley, Michael A., Munoz, Benito, Scherer, Christina A., Duvall, Jeremy R., Schreiber, Stuart L.
Publicado 2014

MTAP deletion confers enhanced dependency on the arginine methyltransferase PRMT5 in human cancer cells

por Kryukov, Gregory V, Wilson, Frederick H, Ruth, Jason R, Paulk, Joshiawa, Tsherniak, Aviad, Marlow, Sara E, Vazquez, Francisca, Weir, Barbara A, Fitzgerald, Mark E, Tanaka, Minoru, Bielski, Craig M, Scott, Justin M, Dennis, Courtney, Cowley, Glenn S, Boehm, Jesse S, Root, David E, Golub, Todd R, Clish, Clary B, Bradner, James E, Hahn, William C, Garraway, Levi A
Publicado en Science (2016)

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

por Heidebrecht, Richard W., Mulrooney, Carol, Austin, Christopher P., Barker, Robert H., Beaudoin, Jennifer A., Cheng, Ken Chih-Chien, Comer, Eamon, Dandapani, Sivaraman, Dick, Justin, Duvall, Jeremy R., Ekland, Eric H., Fidock, David A., Fitzgerald, Mark E., Foley, Michael, Guha, Rajarshi, Hinkson, Paul, Kramer, Martin, Lukens, Amanda K., Masi, Daniela, Marcaurelle, Lisa A., Su, Xin-Zhuan, Thomas, Craig J., Weïwer, Michel, Wiegand, Roger C., Wirth, Dyann, Xia, Menghang, Yuan, Jing, Zhao, Jinghua, Palmer, Michelle, Munoz, Benito, Schreiber, Stuart
Publicado 2011