A Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization

A build/couple/pair (B/C/P) strategy was employed to generate a library of 7936 stereochemically diverse 12-membered macrolactams. All 8 stereoisomers of a common linear amine precursor were elaborated to form the corresponding 8 stereoisomers of two regioisomeric macrocyclic scaffolds via head-to-t...

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Detaylı Bibliyografya
Asıl Yazarlar: Fitzgerald, Mark E., Mulrooney, Carol A., Duvall, Jeremy R., Wei, Jingqiang, Suh, Byung-Chul, Akella, Lakshmi B., Vrcic, Anita, Marcaurelle, Lisa A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289975/
https://ncbi.nlm.nih.gov/pubmed/22252910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co200161z
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