Optical control of GPR40 signalling in pancreatic β-cells

por Frank, James Allen, Yushchenko, Dmytro A., Fine, Nicholas H. F., Duca, Margherita, Citir, Mevlut, Broichhagen, Johannes, Hodson, David J., Schultz, Carsten, Trauner, Dirk
Publicado en Chem Sci (2017)

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

por Podewin, Tom, Broichhagen, Johannes, Frost, Christina, Groneberg, Dieter, Ast, Julia, Meyer-Berg, Helena, Fine, Nicholas H. F., Friebe, Andreas, Zacharias, Martin, Hodson, David J., Trauner, Dirk, Hoffmann-Röder, Anja
Publicado en Chem Sci (2017)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice

por Mehta, Zenobia B., Fine, Nicholas, Pullen, Timothy J., Cane, Matthew C., Hu, Ming, Chabosseau, Pauline, Meur, Gargi, Velayos-Baeza, Antonio, Monaco, Anthony P., Marselli, Lorella, Marchetti, Piero, Rutter, Guy A.
Publicado en Am J Physiol Endocrinol Metab (2016)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

por Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Publicado en Diabetes (2018)

Dimerization of the Sodium/Iodide Symporter

por Thompson, Rebecca J., Fletcher, Alice, Brookes, Katie, Nieto, Hannah, Alshahrani, Mohammed M., Mueller, Jonathan W., Fine, Nicholas H.F., Hodson, David J., Boelaert, Kristien, Read, Martin L., Smith, Vicki E., McCabe, Christopher J.
Publicado en Thyroid (2019)

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

por Seabright, Alex P., Fine, Nicholas H. F., Barlow, Jonathan P., Lord, Samuel O., Musa, Ibrahim, Gray, Alexander, Bryant, Jack A., Banzhaf, Manuel, Lavery, Gareth G., Hardie, D. Grahame, Hodson, David J., Philp, Andrew, Lai, Yu‐Chiang
Publicado en FASEB J (2020)

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

por Podewin, Tom, Ast, Julia, Broichhagen, Johannes, Fine, Nicholas H. F., Nasteska, Daniela, Leippe, Philipp, Gailer, Manuel, Buenaventura, Teresa, Kanda, Nisha, Jones, Ben J., M’Kadmi, Celine, Baneres, Jean-Louis, Marie, Jacky, Tomas, Alejandra, Trauner, Dirk, Hoffmann-Röder, Anja, Hodson, David J.
Publicado en ACS Cent Sci (2018)

PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

por Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Publicado en Nat Commun (2021)

Author Correction: PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

por Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Publicado en Nat Commun (2021)

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

por Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Publicado en Diabetologia (2019)

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

por Navarro, Guadalupe, Allard, Camille, Morford, Jamie J., Xu, Weiwei, Liu, Suhuan, Molinas, Adrien J.R., Butcher, Sierra M., Fine, Nicholas H.F., Blandino-Rosano, Manuel, Sure, Venkata N., Yu, Sangho, Zhang, Rui, Münzberg, Heike, Jacobson, David A., Katakam, Prasad V., Hodson, David J., Bernal-Mizrachi, Ernesto, Zsombok, Andrea, Mauvais-Jarvis, Franck
Publicado en JCI Insight (2018)

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

por Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.
Publicado en Cell Rep (2020)

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

por Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Publicado en Nat Commun (2020)

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

por Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Publicado en Nat Commun (2020)

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

por Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.
Publicado en Diabetologia (2021)