Optical control of GPR40 signalling in pancreatic β-cells

Autor Frank, James Allen, Yushchenko, Dmytro A., Fine, Nicholas H. F., Duca, Margherita, Citir, Mevlut, Broichhagen, Johannes, Hodson, David J., Schultz, Carsten, Trauner, Dirk
Vydáno v Chem Sci (2017)

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Autor Podewin, Tom, Broichhagen, Johannes, Frost, Christina, Groneberg, Dieter, Ast, Julia, Meyer-Berg, Helena, Fine, Nicholas H. F., Friebe, Andreas, Zacharias, Martin, Hodson, David J., Trauner, Dirk, Hoffmann-Röder, Anja
Vydáno v Chem Sci (2017)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice

Autor Mehta, Zenobia B., Fine, Nicholas, Pullen, Timothy J., Cane, Matthew C., Hu, Ming, Chabosseau, Pauline, Meur, Gargi, Velayos-Baeza, Antonio, Monaco, Anthony P., Marselli, Lorella, Marchetti, Piero, Rutter, Guy A.
Vydáno v Am J Physiol Endocrinol Metab (2016)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Autor Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Vydáno v Diabetes (2018)

Dimerization of the Sodium/Iodide Symporter

Autor Thompson, Rebecca J., Fletcher, Alice, Brookes, Katie, Nieto, Hannah, Alshahrani, Mohammed M., Mueller, Jonathan W., Fine, Nicholas H.F., Hodson, David J., Boelaert, Kristien, Read, Martin L., Smith, Vicki E., McCabe, Christopher J.
Vydáno v Thyroid (2019)

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

Autor Seabright, Alex P., Fine, Nicholas H. F., Barlow, Jonathan P., Lord, Samuel O., Musa, Ibrahim, Gray, Alexander, Bryant, Jack A., Banzhaf, Manuel, Lavery, Gareth G., Hardie, D. Grahame, Hodson, David J., Philp, Andrew, Lai, Yu‐Chiang
Vydáno v FASEB J (2020)

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

Autor Podewin, Tom, Ast, Julia, Broichhagen, Johannes, Fine, Nicholas H. F., Nasteska, Daniela, Leippe, Philipp, Gailer, Manuel, Buenaventura, Teresa, Kanda, Nisha, Jones, Ben J., M’Kadmi, Celine, Baneres, Jean-Louis, Marie, Jacky, Tomas, Alejandra, Trauner, Dirk, Hoffmann-Röder, Anja, Hodson, David J.
Vydáno v ACS Cent Sci (2018)

PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

Autor Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Vydáno v Nat Commun (2021)

Author Correction: PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

Autor Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Vydáno v Nat Commun (2021)

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

Autor Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Vydáno v Diabetologia (2019)

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

Autor Navarro, Guadalupe, Allard, Camille, Morford, Jamie J., Xu, Weiwei, Liu, Suhuan, Molinas, Adrien J.R., Butcher, Sierra M., Fine, Nicholas H.F., Blandino-Rosano, Manuel, Sure, Venkata N., Yu, Sangho, Zhang, Rui, Münzberg, Heike, Jacobson, David A., Katakam, Prasad V., Hodson, David J., Bernal-Mizrachi, Ernesto, Zsombok, Andrea, Mauvais-Jarvis, Franck
Vydáno v JCI Insight (2018)

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

Autor Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.
Vydáno v Cell Rep (2020)

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Autor Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Vydáno v Nat Commun (2020)

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Autor Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Vydáno v Nat Commun (2020)

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

Autor Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.
Vydáno v Diabetologia (2021)