Conserved core of amyloid fibrils of wild type and A30P mutant α-synuclein

Por Cho, Min-Kyu, Kim, Hai-Young, Fernandez, Claudio O, Becker, Stefan, Zweckstetter, Markus
Publicado em 2011

Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics

Por Villar-Piqué, Anna, Rossetti, Giulia, Ventura, Salvador, Carloni, Paolo, Fernández, Claudio O., Outeiro, Tiago Fleming
Publicado no Commun Integr Biol (2017)

NMR of α-synuclein–polyamine complexes elucidates the mechanism and kinetics of induced aggregation

Por Fernández, Claudio O, Hoyer, Wolfgang, Zweckstetter, Markus, Jares-Erijman, Elizabeth A, Subramaniam, Vinod, Griesinger, Christian, Jovin, Thomas M
Publicado em 2004

Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein

Por Bertoncini, Carlos W., Jung, Young-Sang, Fernandez, Claudio O., Hoyer, Wolfgang, Griesinger, Christian, Jovin, Thomas M., Zweckstetter, Markus
Publicado em 2005

Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation

Por Lamberto, Gonzalo R., Binolfi, Andrés, Orcellet, María L., Bertoncini, Carlos W., Zweckstetter, Markus, Griesinger, Christian, Fernández, Claudio O.
Publicado em 2009

Toward the Discovery of Effective Polycyclic Inhibitors of α-Synuclein Amyloid Assembly

Por Lamberto, Gonzalo R., Torres-Monserrat, Valentina, Bertoncini, Carlos W., Salvatella, Xavier, Zweckstetter, Markus, Griesinger, Christian, Fernández, Claudio O.
Publicado em 2011

Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation

Por Valiente-Gabioud, Ariel A., Riedel, Dietmar, Outeiro, Tiago F., Menacho-Márquez, Mauricio A., Griesinger, Christian, Fernández, Claudio O.
Publicado no Biophys J (2018)

Structural characterization of copper(II) binding to α-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease

Por Rasia, Rodolfo M., Bertoncini, Carlos W., Marsh, Derek, Hoyer, Wolfgang, Cherny, Dmitry, Zweckstetter, Markus, Griesinger, Christian, Jovin, Thomas M., Fernández, Claudio O.
Publicado em 2005

Structural characterization of α-synuclein in an aggregation prone state

Por Cho, Min-Kyu, Nodet, Gabrielle, Kim, Hai-Young, Jensen, Malene R, Bernado, Pau, Fernandez, Claudio O, Becker, Stefan, Blackledge, Martin, Zweckstetter, Markus
Publicado em 2009

Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106–115

Por Arcos-López, Trinidad, Qayyum, Munzarin, Rivillas-Acevedo, Lina, Miotto, Marco C., Grande-Aztatzi, Rafael, Fernández, Claudio O., Hedman, Britt, Hodgson, Keith O., Vela, Alberto, Solomon, Edward I., Quintanar, Liliana
Publicado no Inorg Chem (2016)

Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein

Por Paleologou, Katerina E., Schmid, Adrian W., Rospigliosi, Carla C., Kim, Hai-Young, Lamberto, Gonzalo R., Fredenburg, Ross A., Lansbury, Peter T., Fernandez, Claudio O., Eliezer, David, Zweckstetter, Markus, Lashuel, Hilal A.
Publicado em 2008

Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species

Por González-Lizárraga, Florencia, Socías, Sergio B., Ávila, César L., Torres-Bugeau, Clarisa M., Barbosa, Leandro R. S., Binolfi, Andres, Sepúlveda-Díaz, Julia E., Del-Bel, Elaine, Fernandez, Claudio O., Papy-Garcia, Dulce, Itri, Rosangela, Raisman-Vozari, Rita, Chehín, Rosana N.
Publicado no Sci Rep (2017)

Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits α-Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions

Por Paleologou, Katerina E., Oueslati, Abid, Shakked, Gideon, Rospigliosi, Carla C., Kim, Hai-Young, Lamberto, Gonzalo R., Fernandez, Claudio O., Schmid, Adrian, Chegini, Fariba, Gai, Wei Ping, Chiappe, Diego, Moniatte, Marc, Schneider, Bernard L., Aebischer, Patrick, Eliezer, David, Zweckstetter, Markus, Masliah, Eliezer, Lashuel, Hilal A.
Publicado em 2010

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity

Por Villar-Piqué, Anna, Lopes da Fonseca, Tomás, Sant’Anna, Ricardo, Szegö, Éva Mónika, Fonseca-Ornelas, Luis, Pinho, Raquel, Carija, Anita, Gerhardt, Ellen, Masaracchia, Caterina, Abad Gonzalez, Enrique, Rossetti, Giulia, Carloni, Paolo, Fernández, Claudio O., Foguel, Debora, Milosevic, Ira, Zweckstetter, Markus, Ventura, Salvador, Outeiro, Tiago Fleming
Publicado no Proc Natl Acad Sci U S A (2016)