Monitoring human exposure to 2-hydroxyethylating carcinogens.

Por Farmer, P B, Cordero, R, Autrup, H
Publicado em 1996

Evaluation of biomarkers in plasma, blood, and urine samples from coke oven workers: significance of exposure to polycyclic aromatic hydrocarbons.

Por Ovrebø, S, Haugen, A, Farmer, P B, Anderson, D
Publicado em 1995

Formation of N-alkylated protoporphyrin IX in the livers of mice after diethylnitrosamine treatment.

Por White, I N, Smith, A G, Farmer, P B
Publicado em 1983

Monitoring exposure to 4,4'-methylene-bis(2-chloroaniline) through the gas chromatography-mass spectrometry measurement of adducts to hemoglobin.

Por Bailey, E, Brooks, A G, Farmer, P B, Street, B
Publicado em 1993

The alkylation of 2′-deoxyguanosine and of thymidine with diazoalkanes. Some observations on O-alkylation

Por Farmer, P. B., Foster, A. B., Jarman, M., Tisdale, M. J.
Publicado em 1973

Isolation and characterization of protoporphyrin glycoconjugates from rat harderian gland by HPLC, capillary electrophoresis and HPLC/electrospray ionization MS.

Por Lim, C K, Razzaque, M A, Luo, J, Farmer, P B
Publicado em 2000

Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O(4)-methyl-thymid...

Por Lawley, P. D., Orr, D. J., Shah, S. A., Farmer, P. B., Jarman, M.
Publicado em 1973

Metabolic activation of acetylenes. Covalent binding of [1,2-14C]octyne to protein, DNA and haem in vitro and the protective effects of certain thiol compounds.

Por White, I N, Campbell, J B, Farmer, P B, Bailey, E, Nam, N H, Thang, D C
Publicado em 1984

Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin.

Por Holley, A E, Frater, Y, Gibbs, A H, De Matteis, F, Lamb, J H, Farmer, P B, Naylor, S
Publicado em 1991

Identification of endogenous electrophiles by means of mass spectrometric determination of protein and DNA adducts.

Por Farmer, P B, Bailey, E, Naylor, S, Anderson, D, Brooks, A, Cushnir, J, Lamb, J H, Sepai, O, Tang, Y S
Publicado em 1993

Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta.

Por Manchester, D K, Weston, A, Choi, J S, Trivers, G E, Fennessey, P V, Quintana, E, Farmer, P B, Mann, D L, Harris, C C
Publicado em 1988

A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.

Por Judah, D J, Hayes, J D, Yang, J C, Lian, L Y, Roberts, G C, Farmer, P B, Lamb, J H, Neal, G E
Publicado em 1993

Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration

Por Garcea, G, Jones, D J L, Singh, R, Dennison, A R, Farmer, P B, Sharma, R A, Steward, W P, Gescher, A J, Berry, D P
Publicado em 2004

Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity

Por Jones, D J L, Lamb, J H, Verschoyle, R D, Howells, L M, Butterworth, M, Lim, C K, Ferry, D, Farmer, P B, Gescher, A J
Publicado em 2004

Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene

Por Sale, S, Verschoyle, R D, Boocock, D, Jones, D J L, Wilsher, N, Ruparelia, K C, Potter, G A, Farmer, P B, Steward, W P, Gescher, A J
Publicado em 2004

Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo

Por Leong, C-O, Gaskell, M, Martin, E A, Heydon, R T, Farmer, P B, Bibby, M C, Cooper, P A, Double, J A, Bradshaw, T D, Stevens, M F G
Publicado em 2003

The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1

Por Potter, G A, Patterson, L H, Wanogho, E, Perry, P J, Butler, P C, Ijaz, T, Ruparelia, K C, Lamb, J H, Farmer, P B, Stanley, L A, Burke, M D
Publicado em 2002