The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1

Resveratrol is a cancer preventative agent that is found in red wine. Piceatannol is a closely related stilbene that has antileukaemic activity and is also a tyrosine kinase inhibitor. Piceatannol differs from resveratrol by having an additional aromatic hydroxy group. The enzyme CYP1B1 is overexpre...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Potter, G A, Patterson, L H, Wanogho, E, Perry, P J, Butler, P C, Ijaz, T, Ruparelia, K C, Lamb, J H, Farmer, P B, Stanley, L A, Burke, M D
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2002
الموضوعات:
Experimental Therapeutics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375304/
https://ncbi.nlm.nih.gov/pubmed/11875742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600197
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