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A NOVEL TETRAZOLE ANALOGUE OF RESVERATROL IS A POTENT ANTICANCER AGENT

A series of novel tetrazole analogues of resveratrol were synthesized and evaluated for their antileukemic activity against an extensive panel of human cancer cell lines and against the MV4-11 AML cell line. These molecules were designed as drug-like derivatives of the resveratrol analogue DMU-212 a...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Bommagani, Shobanbabu, Penthala, Narsimha Reddy, Balasubramaniam, Meenakshisundaram, Kuravi, Sudhakiranmayi, Caldas-Lopes, Eloisi, Guzman, Monica L., Balusu, Ramesh, Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497071/
https://ncbi.nlm.nih.gov/pubmed/30528695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.12.006
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