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Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin

A series of novel diarylacrylonitrile and trans-stilbene analogues of resveratrol has been synthesized and evaluated for their anticancer activities against a panel of 60 human cancer cell lines. The diarylacrylonitrile analogues 3b and 4a exhibited the most potent anticancer activity of all the ana...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Madadi, Nikhil R., Zong, Hongliang, Ketkar, Amit, Zheng, Chen, Penthala, Narsimha R., Janganati, Venumadhav, Bommagani, Shobanbabu, Eoff, Robert L., Guzman, Monica L., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527554/
https://ncbi.nlm.nih.gov/pubmed/26257861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00478G
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