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Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O(4)-methyl-thymidine

1. DNA was treated with N-methyl-N-nitrosourea at pH7–8, 37°C, degraded to yield 3- and 7-methylpurines and deoxyribonucleosides and the reaction products were separated by chromatography on ion-exchange resins. The following methods for identification and determination of products were used: with u...

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Detaylı Bibliyografya
Asıl Yazarlar: Lawley, P. D., Orr, D. J., Shah, S. A., Farmer, P. B., Jarman, M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1973
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165804/
https://ncbi.nlm.nih.gov/pubmed/4798180
Etiketler: Etiketle
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