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Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea

The reaction of the carcinogen N-methyl-N-nitrosourea with mitochondrial DNA from various rat tissues was examined in vivo and in vitro. After incubation of isolated mitochondria or cell nuclei with N[(14)C]-methyl-N-nitrosourea in vitro and subsequent isolation and purification of the DNA the speci...

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Bibliografiske detaljer
Main Authors: Wunderlich, V., Schütt, M., Böttger, M., Graffi, A.
Format: Artigo
Sprog:Inglês
Udgivet: 1970
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1179086/
https://ncbi.nlm.nih.gov/pubmed/5472159
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