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Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1. N[(14)C]-Methyl-N-nitrosourea, [(14)C]dimethylnitrosamine, [(14)C]dimethyl sulphate and [(14)C]methyl methanesulphonate were injected into rats, and nucleic acids were isolated from several organs after various time-intervals. Radioactivity was detected in DNA and RNA, partly in major base compon...

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Detalles Bibliográficos
Main Authors: Swann, P. F., Magee, P. N.
Formato: Artigo
Idioma:Inglês
Publicado: 1968
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187106/
https://ncbi.nlm.nih.gov/pubmed/5722690
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