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Nitrosamine-induced carcinogenesis. The alkylation of N-7 of guanine of nucleic acids of the rat by diethylnitrosamine, N-ethyl-N-nitrosourea and ethyl methanesulphonate

1. The extent of ethylation of N-7 of guanine in the nucleic acids of rat tissue in vivo by diethylnitrosamine, N-ethyl-N-nitrosourea and ethyl methanesulphonate was measured. 2. All compounds produced measurable amounts of 7-ethyl-guanine. 3. A single dose of diethylnitrosamine or N-ethyl-N-nitroso...

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Main Authors: Swann, P. F., Magee, P. N.
格式: Artigo
語言:Inglês
出版: 1971
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1178189/
https://ncbi.nlm.nih.gov/pubmed/5145908
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