A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.

In contrast with fractions from control animals, an aldehyde reductase, which catalyses the reduction of aflatoxin B1-dihydrodiol, in the dialdehyde form at physiological pH values, to aflatoxin B1-dialcohol, is expressed in cytosolic fractions prepared from rat livers bearing pre-neoplastic lesions...

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Detalhes bibliográficos
Main Authors: Judah, D J, Hayes, J D, Yang, J C, Lian, L Y, Roberts, G C, Farmer, P B, Lamb, J H, Neal, G E
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134261/
https://ncbi.nlm.nih.gov/pubmed/8503840
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