Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution

af Vo, Uybach, Vajpai, Navratna, Embrey, Kevin J., Golovanov, Alexander P.
Udgivet i Sci Rep (2016)

Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A

af Williams, Felix P., Milbradt, Alexander G., Embrey, Kevin J., Bobby, Romel
Udgivet i PLoS One (2016)

Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence

af Vo, Uybach, Vajpai, Navratna, Flavell, Liz, Bobby, Romel, Breeze, Alexander L., Embrey, Kevin J., Golovanov, Alexander P.
Udgivet i J Biol Chem (2016)

Myc phosphorylation in its basic helix–loop–helix region destabilizes transient α-helical structures, disrupting Max and DNA binding

af Macek, Pavel, Cliff, Matthew J., Embrey, Kevin J., Holdgate, Geoffrey A., Nissink, J. Willem M., Panova, Stanislava, Waltho, Jonathan P., Davies, Rick A.
Udgivet i J Biol Chem (2018)

Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition

af Ogden, Tom E H, Yang, Ji-Chun, Schimpl, Marianne, Easton, Laura E, Underwood, Elizabeth, Rawlins, Philip B, McCauley, Michael M, Langelier, Marie-France, Pascal, John M, Embrey, Kevin J, Neuhaus, David
Udgivet i Nucleic Acids Res (2021)

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

af Cohen, E. Suzanne, Scott, Ian C., Majithiya, Jayesh B., Rapley, Laura, Kemp, Benjamin P., England, Elizabeth, Rees, D. Gareth, Overed-Sayer, Catherine L., Woods, Joanne, Bond, Nicholas J., Veyssier, Christel Séguy, Embrey, Kevin J., Sims, Dorothy A., Snaith, Michael R., Vousden, Katherine A., Strain, Martin D., Chan, Denice T. Y., Carmen, Sara, Huntington, Catherine E., Flavell, Liz, Xu, Jianqing, Popovic, Bojana, Brightling, Christopher E., Vaughan, Tristan J., Butler, Robin, Lowe, David C., Higazi, Daniel R., Corkill, Dominic J., May, Richard D., Sleeman, Matthew A., Mustelin, Tomas
Udgivet i Nat Commun (2015)

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

af Tron, Adriana E., Belmonte, Matthew A., Adam, Ammar, Aquila, Brian M., Boise, Lawrence H., Chiarparin, Elisabetta, Cidado, Justin, Embrey, Kevin J., Gangl, Eric, Gibbons, Francis D., Gregory, Gareth P., Hargreaves, David, Hendricks, J. Adam, Johannes, Jeffrey W., Johnstone, Ricky W., Kazmirski, Steven L., Kettle, Jason G., Lamb, Michelle L., Matulis, Shannon M., Nooka, Ajay K., Packer, Martin J., Peng, Bo, Rawlins, Philip B., Robbins, Daniel W., Schuller, Alwin G., Su, Nancy, Yang, Wenzhan, Ye, Qing, Zheng, Xiaolan, Secrist, J. Paul, Clark, Edwin A., Wilson, David M., Fawell, Stephen E., Hird, Alexander W.
Udgivet i Nat Commun (2018)