Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations

Por Porkka, Noora, Valo, Satu, Nieminen, Taina T., Olkinuora, Alisa, Mäki-Nevala, Satu, Eldfors, Samuli, Peltomäki, Päivi
Publicado no Oncotarget (2017)

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Por Alisa Olkinuora, Annette Gylling, Henrikki Almusa, Samuli Eldfors, Anna Lepistö, Jukka-Pekka Mecklin, Taina Tuulikki Nieminen, Päivi Peltomäki
Publicado em 2020-07-01

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

Por Kangaspeska, Sara, Hultsch, Susanne, Jaiswal, Alok, Edgren, Henrik, Mpindi, John-Patrick, Eldfors, Samuli, Brück, Oscar, Aittokallio, Tero, Kallioniemi, Olli
Publicado no BMC Cancer (2016)

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

Por Eldfors, S, Kuusanmäki, H, Kontro, M, Majumder, M M, Parsons, A, Edgren, H, Pemovska, T, Kallioniemi, O, Wennerberg, K, Gökbuget, N, Burmeister, T, Porkka, K, Heckman, C A
Publicado no Leukemia (2017)

Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation

Por Andersson, E I, Rajala, H L M, Eldfors, S, Ellonen, P, Olson, T, Jerez, A, Clemente, M J, Kallioniemi, O, Porkka, K, Heckman, C, Loughran, T P, Maciejewski, J P, Mustjoki, S
Publicado em 2013

Comparison of solution-based exome capture methods for next generation sequencing

Por Sulonen, Anna-Maija, Ellonen, Pekka, Almusa, Henrikki, Lepistö, Maija, Eldfors, Samuli, Hannula, Sari, Miettinen, Timo, Tyynismaa, Henna, Salo, Perttu, Heckman, Caroline, Joensuu, Heikki, Raivio, Taneli, Suomalainen, Anu, Saarela, Janna
Publicado em 2011

Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

Por Malani, D, Murumägi, A, Yadav, B, Kontro, M, Eldfors, S, Kumar, A, Karjalainen, R, Majumder, M M, Ojamies, P, Pemovska, T, Wennerberg, K, Heckman, C, Porkka, K, Wolf, M, Aittokallio, T, Kallioniemi, O
Publicado no Leukemia (2017)

Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

Por Majumder, Muntasir Mamun, Silvennoinen, Raija, Anttila, Pekka, Tamborero, David, Eldfors, Samuli, Yadav, Bhagwan, Karjalainen, Riikka, Kuusanmäki, Heikki, Lievonen, Juha, Parsons, Alun, Suvela, Minna, Jantunen, Esa, Porkka, Kimmo, Heckman, Caroline A.
Publicado no Oncotarget (2017)

Activating somatic mutations outside the SH2-domain of STAT3 in LGL-Leukemia

Por Andersson, Emma, Kuusanmäki, Heikki, Bortoluzzi, Sabrina, Lagström, Sonja, Parsons, Alun, Rajala, Hanna, van Adrichem, Arjan, Eldfors, Samuli, Olson, Thomas, Clemente, Michael J., Laasonen, Anu, Ellonen, Pekka, Heckman, Caroline, Loughran, Thomas P., Maciejewski, Jaroslaw P., Mustjoki, Satu
Publicado no Leukemia (2015)

Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

Por Savola, P., Kelkka, T., Rajala, H. L., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagström, S., Lepistö, M., Hannunen, T., Andersson, E. I., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M., Mustjoki, S.
Publicado no Nat Commun (2017)

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Por Rajala, Hanna L. M., Eldfors, Samuli, Kuusanmäki, Heikki, van Adrichem, Arjan J., Olson, Thomas, Lagström, Sonja, Andersson, Emma I., Jerez, Andres, Clemente, Michael J., Yan, Yiyi, Zhang, Dan, Awwad, Andy, Ellonen, Pekka, Kallioniemi, Olli, Wennerberg, Krister, Porkka, Kimmo, Maciejewski, Jaroslaw P., Loughran, Thomas P., Heckman, Caroline, Mustjoki, Satu
Publicado em 2013

High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia

Por Andersson, Emma I., Tanahashi, Takahiro, Sekiguchi, Nodoka, Gasparini, Vanessa Rebecca, Bortoluzzi, Sabrina, Kawakami, Toru, Matsuda, Kazuyuki, Mitsui, Takeki, Eldfors, Samuli, Bortoluzzi, Stefania, Coppe, Alessandro, Binatti, Andrea, Lagström, Sonja, Ellonen, Pekka, Fukushima, Noriyasu, Nishina, Sayaka, Senoo, Noriko, Sakai, Hitoshi, Nakazawa, Hideyuki, Kwong, Yok-Lam, Loughran, Thomas P., Maciejewski, Jaroslaw P., Mustjoki, Satu, Ishida, Fumihiro
Publicado no Blood (2016)

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Por Dufva, Olli, Kankainen, Matti, Kelkka, Tiina, Sekiguchi, Nodoka, Awad, Shady Adnan, Eldfors, Samuli, Yadav, Bhagwan, Kuusanmäki, Heikki, Malani, Disha, Andersson, Emma I, Pietarinen, Paavo, Saikko, Leena, Kovanen, Panu E., Ojala, Teija, Lee, Dean A., Loughran, Thomas P., Nakazawa, Hideyuki, Suzumiya, Junji, Suzuki, Ritsuro, Ko, Young Hyeh, Kim, Won Seog, Chuang, Shih-Sung, Aittokallio, Tero, Chan, Wing C., Ohshima, Koichi, Ishida, Fumihiro, Mustjoki, Satu
Publicado no Nat Commun (2018)

Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3

Por Haapaniemi, Emma M., Kaustio, Meri, Rajala, Hanna L. M., van Adrichem, Arjan J., Kainulainen, Leena, Glumoff, Virpi, Doffinger, Rainer, Kuusanmäki, Heikki, Heiskanen-Kosma, Tarja, Trotta, Luca, Chiang, Samuel, Kulmala, Petri, Eldfors, Samuli, Katainen, Riku, Siitonen, Sanna, Karjalainen-Lindsberg, Marja-Liisa, Kovanen, Panu E., Otonkoski, Timo, Porkka, Kimmo, Heiskanen, Kaarina, Hänninen, Arno, Bryceson, Yenan T., Uusitalo-Seppälä, Raija, Saarela, Janna, Seppänen, Mikko, Mustjoki, Satu, Kere, Juha
Publicado no Blood (2015)

Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

Por Koskela, Hanna L.M., Eldfors, Samuli, Ellonen, Pekka, van Adrichem, Arjan J., Kuusanmäki, Heikki, Andersson, Emma I., Lagström, Sonja, Clemente, Michael J., Olson, Thomas, Jalkanen, Sari E., Majumder, Muntasir Mamun, Almusa, Henrikki, Edgren, Henrik, Lepistö, Maija, Mattila, Pirkko, Guinta, Kathryn, Koistinen, Pirjo, Kuittinen, Taru, Penttinen, Kati, Parsons, Alun, Knowles, Jonathan, Saarela, Janna, Wennerberg, Krister, Kallioniemi, Olli, Porkka, Kimmo, Loughran, Thomas P., Heckman, Caroline A., Maciejewski, Jaroslaw P., Mustjoki, Satu
Publicado em 2012