SIGN: similarity identification in gene expression

por Madani Tonekaboni, Seyed Ali, Manem, Venkata Satya Kumar, El-Hachem, Nehme, Haibe-Kains, Benjamin
Publicado no Bioinformatics (2019)

Regulation of De Novo Ceramide Synthesis: The Role of Dihydroceramide Desaturase and Transcriptional Factors NFATC and Hand2 in the Hypoxic Mouse Heart

por Azzam, Raed, Hariri, Fadi, El-Hachem, Nehmé, Kamar, Amina, Dbaibo, Ghassan, Nemer, Georges, Bitar, Fadi
Publicado em 2013

A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases

por Khalil, Athar, Tanos, Rachel, El-Hachem, Nehmé, Kurban, Mazen, Bouvagnet, Patrice, Bitar, Fadi, Nemer, Georges
Publicado no Sci Rep (2017)

Importance of collection in gene set enrichment analysis of drug response in cancer cell lines

por Bateman, Alain R., El-Hachem, Nehme, Beck, Andrew H., Aerts, Hugo J. W. L., Haibe-Kains, Benjamin
Publicado em 2014

Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes

por Khalil, Athar, Dekmak, Batoul, Boulos, Fouad, Kantrowitz, Jake, Spira, Avrum, Fujimoto, Junya, Kadara, Humam, El-Hachem, Nehme, Nemer, Georges
Publicado no Front Oncol (2018)

Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells

por Bikorimana, Jean-Pierre, El-Hachem, Nehme, El-Kadiry, Abed El-Hakim, Abusarah, Jamilah, Salame, Natasha, Shammaa, Riam, Rafei, Moutih
Publicado no Front Immunol (2021)

A comparison of artificial intelligence-based algorithms for the identification of patients with depressed right ventricular function from 2-dimentional echocardiography parameters...

por Ahmad, Ali, Ibrahim, Zahi, Sakr, Georges, El-Bizri, Abdallah, Masri, Lara, Elhajj, Imad H., El-Hachem, Nehme, Isma’eel, Hussain
Publicado no Cardiovasc Diagn Ther (2020)

Inconsistency in large pharmacogenomic studies

por Haibe-Kains, Benjamin, El-Hachem, Nehme, Birkbak, Nicolai Juul, Jin, Andrew C., Beck, Andrew H., Aerts, Hugo J.W.L., Quackenbush, John
Publicado no Nature (2013)

Tissue specificity of in vitro drug sensitivity

por Yao, Fupan, Madani Tonekaboni, Seyed Ali, Safikhani, Zhaleh, Smirnov, Petr, El-Hachem, Nehme, Freeman, Mark, Manem, Venkata Satya Kumar, Haibe-Kains, Benjamin
Publicado no J Am Med Inform Assoc (2017)

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer

por Goyette, Marie-Anne, Cusseddu, Rebecca, Elkholi, Islam, Abu-Thuraia, Afnan, El-Hachem, Nehme, Haibe-Kains, Benjamin, Gratton, Jean-Philippe, Côté, Jean-François
Publicado no Oncotarget (2019)

Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms

por El-Hachem, Nehme, Grossmann, Patrick, Blanchet-Cohen, Alexis, Bateman, Alain R., Bouchard, Nicolas, Archambault, Jacques, Aerts, Hugo J.W.L., Haibe-Kains, Benjamin
Publicado no Environ Health Perspect (2015)

Gene isoforms as expression-based biomarkers predictive of drug response in vitro

por Safikhani, Zhaleh, Smirnov, Petr, Thu, Kelsie L., Silvester, Jennifer, El-Hachem, Nehme, Quevedo, Rene, Lupien, Mathieu, Mak, Tak W., Cescon, David, Haibe-Kains, Benjamin
Publicado no Nat Commun (2017)

PharmacoDB: an integrative database for mining in vitro anticancer drug screening studies

por Smirnov, Petr, Kofia, Victor, Maru, Alexander, Freeman, Mark, Ho, Chantal, El-Hachem, Nehme, Adam, George-Alexandru, Ba-alawi, Wail, Safikhani, Zhaleh, Haibe-Kains, Benjamin
Publicado no Nucleic Acids Res (2018)

Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro

por Safikhani, Zhaleh, Smirnov, Petr, Thu, Kelsie L., Silvester, Jennifer, El-Hachem, Nehme, Quevedo, Rene, Lupien, Mathieu, Mak, Tak W., Cescon, David, Haibe-Kains, Benjamin
Publicado no Nat Commun (2018)

New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity

por Hirz, Taghreed, Khalaf, Ali, El-Hachem, Nehme, Mrad, May F, Abdallah, Hassan, Créminon, Christophe, Grée, René, Merhi, Raghida Abou, Habib, Aïda, Hachem, Ali, Hamade, Eva
Publicado em 2012

Assessment of pharmacogenomic agreement

por Safikhani, Zhaleh, El-Hachem, Nehme, Quevedo, Rene, Smirnov, Petr, Goldenberg, Anna, Juul Birkbak, Nicolai, Mason, Christopher, Hatzis, Christos, Shi, Leming, Aerts, Hugo JWL, Quackenbush, John, Haibe-Kains, Benjamin
Publicado no F1000Res (2016)

A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties

por El-Kadiry, Abed El-Hakim, Abusarah, Jamilah, Cui, Yun Emma, El-Hachem, Nehme, Hammond-Martel, Ian, Wurtele, Hugo, Thomas, Sini, Ahmadi, Maryam, Balood, Mohammad, Talbot, Sébastien, Rafei, Moutih
Publicado no Front Pharmacol (2020)

Defining the biological basis of radiomic phenotypes in lung cancer

por Grossmann, Patrick, Stringfield, Olya, El-Hachem, Nehme, Bui, Marilyn M, Rios Velazquez, Emmanuel, Parmar, Chintan, Leijenaar, Ralph TH, Haibe-Kains, Benjamin, Lambin, Philippe, Gillies, Robert J, Aerts, Hugo JWL
Publicado no eLife (2017)

gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect

por Ayoub, Abeer J., Hariss, Layal, El-Hachem, Nehme, El-Achkar, Ghewa A., Ghayad, Sandra E., Dagher, Oula K., Borghol, Nada, Grée, René, Badran, Bassam, Hachem, Ali, Hamade, Eva, Habib, Aida
Publicado no BMC Chem (2019)

Integrative Transcriptome Analyses Empower the Anti-COVID-19 Drug Arsenal

por El-Hachem, Nehme, Eid, Edward, Nemer, Georges, Dbaibo, Ghassan, Abbas, Ossama, Rubeiz, Nelly, Zeineldine, Salah, Matar, Ghassan M., Bikorimana, Jean-Pierre, Shammaa, Riam, Haibe-Kains, Benjamin, Kurban, Mazen, Rafei, Moutih
Publicado no iScience (2020)