AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer

Triple-Negative Breast Cancer (TNBC) is an aggressive cancer subtype that is associated with a poor prognosis due to its propensity to form metastases. The receptor tyrosine kinase AXL plays a role in tumor cell dissemination and its expression in breast cancers correlates with poor patient survival...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Goyette, Marie-Anne, Cusseddu, Rebecca, Elkholi, Islam, Abu-Thuraia, Afnan, El-Hachem, Nehme, Haibe-Kains, Benjamin, Gratton, Jean-Philippe, Côté, Jean-François
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459349/
https://ncbi.nlm.nih.gov/pubmed/31007848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26725
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