Tissue specificity of in vitro drug sensitivity

OBJECTIVES: We sought to investigate the tissue specificity of drug sensitivities in large-scale pharmacological studies and compare these associations to those found in drug clinical indications. MATERIALS AND METHODS: We leveraged the curated cell line response data from PharmacoGx and applied an...

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Bibliografski detalji
Izdano u:J Am Med Inform Assoc
Glavni autori: Yao, Fupan, Madani Tonekaboni, Seyed Ali, Safikhani, Zhaleh, Smirnov, Petr, El-Hachem, Nehme, Freeman, Mark, Manem, Venkata Satya Kumar, Haibe-Kains, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Research and Applications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381764/
https://ncbi.nlm.nih.gov/pubmed/29016819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocx062
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