Tissue specificity of in vitro drug sensitivity

OBJECTIVES: We sought to investigate the tissue specificity of drug sensitivities in large-scale pharmacological studies and compare these associations to those found in drug clinical indications. MATERIALS AND METHODS: We leveraged the curated cell line response data from PharmacoGx and applied an...

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Dades bibliogràfiques
Publicat a:J Am Med Inform Assoc
Autors principals: Yao, Fupan, Madani Tonekaboni, Seyed Ali, Safikhani, Zhaleh, Smirnov, Petr, El-Hachem, Nehme, Freeman, Mark, Manem, Venkata Satya Kumar, Haibe-Kains, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Research and Applications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381764/
https://ncbi.nlm.nih.gov/pubmed/29016819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocx062
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