Matrix-Dependent Perturbation of TGFβ Signaling and Disease

Por Doyle, Jefferson J., Gerber, Elizabeth E., Dietz, Harry C.
Publicado em 2012

Transforming Growth Factor-β Signaling Pathway Activation in Keratoconus

Por ENGLER, CHRISTOPH, CHAKRAVARTI, SHUKTI, DOYLE, JEFFERSON, EBERHART, CHARLES G., MENG, HUAN, STARK, WALTER J., KELLIHER, CLARE, JUN, ALBERT S.
Publicado em 2011

Targeting collagen strands by photo-triggered triple-helix hybridization

Por Li, Yang, Foss, Catherine A., Summerfield, Daniel D., Doyle, Jefferson J., Torok, Collin M., Dietz, Harry C., Pomper, Martin G., Yu, S. Michael
Publicado em 2012

Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism

Por Habashi, Jennifer P., Doyle, Jefferson J., Holm, Tammy M., Aziz, Hamza, Schoenhoff, Florian, Bedja, Djahida, Chen, YiChun, Modiri, Alexandra N., Judge, Daniel P., Dietz, Harry C.
Publicado em 2011

Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

Por Holm, Tammy M., Habashi, Jennifer P., Doyle, Jefferson J., Bedja, Djahida, Chen, YiChun, van Erp, Christel, Lindsay, Mark E., Kim, David, Schoenhoff, Florian, Cohn, Ronald D., Loeys, Bart L., Thomas, Craig J., Patnaik, Samarjit, Marugan, Juan J., Judge, Daniel P., Dietz, Harry C.
Publicado em 2011

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

Por Doyle, Jefferson J, Doyle, Alexander J, Wilson, Nicole K, Habashi, Jennifer P, Bedja, Djahida, Whitworth, Ryan E, Lindsay, Mark E, Schoenhoff, Florian, Myers, Loretha, Huso, Nick, Bachir, Suha, Squires, Oliver, Rusholme, Benjamin, Ehsan, Hamid, Huso, David, Thomas, Craig J, Caulfield, Mark J, Van Eyk, Jennifer E, Judge, Daniel P, Dietz, Harry C
Publicado no eLife (2015)

Mutations in the TGF-β Repressor SKI Cause Shprintzen-Goldberg Syndrome with Aortic Aneurysm

Por Doyle, Alexander J., Doyle, Jefferson J., Bessling, Seneca L., Maragh, Samantha, Lindsay, Mark E., Schepers, Dorien, Gillis, Elisabeth, Mortier, Geert, Homfray, Tessa, Sauls, Kimberly, Norris, Russell A., Huso, Nicholas D., Leahy, Dan, Mohr, David W., Caulfield, Mark J., Scott, Alan F., Destrée, Anne, Hennekam, Raoul C., Arn, Pamela H., Curry, Cynthia J., Van Laer, Lut, McCallion, Andrew S., Loeys, Bart L., Dietz, Harry C.
Publicado em 2012

Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

Por Lindsay, Mark E., Schepers, Dorien, Ajit Bolar, Nikhita, Doyle, Jefferson, Gallo, Elena, Fert-Bober, Justyna, Kempers, Marlies J.E., Fishman, Elliot K., Chen, Yichun, Myers, Loretha, Bjeda, Djahita, Oswald, Gretchen, Elias, Abdullah F., Levy, Howard P., Anderlid, Britt-Marie, Yang, Margaret H., Bongers, Ernie M.H.F., Timmermans, Janneke, Braverman, Alan C., Canham, Natalie, Mortier, Geert R., Brunner, Han G., Byers, Peter H., Van Eyk, Jennifer, Van Laer, Lut, Dietz, Harry C., Loeys, Bart L.
Publicado em 2012