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Matrix-Dependent Perturbation of TGFβ Signaling and Disease

Transforming growth factor beta (TGFβ) is a multipotent cytokine that is sequestered in the extracellular matrix (ECM) through interactions with a number of ECM proteins. The ECM serves to concentrate latent TGFβ at sites of intended function, to influence the bioavailability and/or function of TGFβ...

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Autors principals: Doyle, Jefferson J., Gerber, Elizabeth E., Dietz, Harry C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426037/
https://ncbi.nlm.nih.gov/pubmed/22641039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.05.027
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