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Targeting the TGFβ signalling pathway in disease

Many drugs that target transforming growth factor-β (TGFβ) signalling have disease applications. Preclinical and clinical studies indicate the utility of these agents in fibrosis and oncology, particularly in augmentation of existing cancer therapies, such as radiation and chemotherapy, as well as i...

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Detalhes bibliográficos
Main Authors: Akhurst, Rosemary J., Hata, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520610/
https://ncbi.nlm.nih.gov/pubmed/23000686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3810
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