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Complexities of TGF-β Targeted Cancer Therapy
Many advanced tumors produce excessive amounts of Transforming Growth Factor-β (TGF-β) which, in normal epithelial cells, is a potent growth inhibitor. However, in oncogenically activated cells, the homeostatic action of TGF-β is often diverted along alternative pathways. Hence, TGF-β signaling elic...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ivyspring International Publisher
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399319/ https://ncbi.nlm.nih.gov/pubmed/22811618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4564 |
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