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Complexities of TGF-β Targeted Cancer Therapy
Many advanced tumors produce excessive amounts of Transforming Growth Factor-β (TGF-β) which, in normal epithelial cells, is a potent growth inhibitor. However, in oncogenically activated cells, the homeostatic action of TGF-β is often diverted along alternative pathways. Hence, TGF-β signaling elic...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Ivyspring International Publisher
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399319/ https://ncbi.nlm.nih.gov/pubmed/22811618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4564 |
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