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The complexities of TGF-β action during mammary and squamous cell carcinogenesis

Many advanced tumors produce excess amounts of Transforming Growth Factor-β (TGF-β), which is a potent growth inhibitor of normal epithelial cells. However, in tumors its homeostatic action on cells can be diverted along several alternative pathways. Thus, TGF-β signaling has been reported to elicit...

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Detalhes bibliográficos
Main Authors: Connolly, Erin C., Akhurst, Rosemary J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520605/
https://ncbi.nlm.nih.gov/pubmed/21619543
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